Transgene and PersonGen Announce Collaboration to Evaluate a New Combination Therapy Against Solid Tumors

information fournie par Boursorama CP •18/01/2022 à 17:45

Collaboration to Evaluate the Combination of Transgene’s Oncolytic Virus and PersonGen’s CAR-T Cells in Preclinical Models

Strasbourg, France, and Suzhou, China, January 18, 2022, 5:45 pm CET – Transgene (Euronext Paris: TNG), a biotech company that designs and develops virus-based immunotherapeutics against cancer, and PersonGen BioTherapeutics, a Chinese biotech company at clinical trial stage, which is developing breakthrough and innovative CAR-T cell therapies for solid tumors and hematologic tumors, today announced a strategic collaboration to evaluate the feasibility and efficacy of combination therapy associating PersonGen's TAA06 CAR-T cell injection with intravenous (IV) administration of an armed oncolytic virus, from Transgene’s Invir.IO™ platform, in solid tumors including pancreatic cancer and brain glioma. The collaboration aims to demonstrate the combination’s likely synergistic mechanisms to potentiate CAR-T cell therapy.

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